bacillus calmette-guerin vaccine-induced lupus vulgaris in a child with trisomy 9

نویسندگان

zahra movahedi department of pediatric infectious disease, school of medicine, qom university of medical sciences and health services, qom, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی قم (qom university of medical sciences)

soheila sotoudeh department 0f dermatology, school of medicine, tehran university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)

setareh mamishi department of pediatric infectious disease, school of medicine, tehran university of medical sciences, tehran, ir iran; pediatrics infectious diseases research center, tehran university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)

farah sabouni department of pediatric infectious disease, school of medicine, tehran university of medical sciences, tehran, ir iran; pediatrics infectious diseases research center, tehran university of medical sciences, tehran, ir iran; department of pediatric infectious disease, school of medicine, tehran university of medical sciences, tehran, ir iran. tel: +98-2166428996, fax: +98-2166428996سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)

چکیده

conclusions post immunization lv is a rare complication of the bcg vaccine and should be considered by any physician. lupus vulgaris is a paucibacillary form of tb. therefore, acid fast bacilli are not detected in most cases. the pcr is a useful method for confirmation of the diagnosis of lv. introduction lupus vulgaris (lv) is one type of cutaneous tuberculosis (tb) but a rare complication of (bcg) vaccination. case presentation we report a 13-month-old boy with trisomy 9 who developed lv on his right arm with extension to anterior part of the chest one month after bcg vaccination. culture and gram stain was negative for mycobacteria. the diagnosis was confirmed by clinical and histopathological correlation and eventually mycobacterium bovis was detected in tissues using the polymerase chain reaction (pcr) method. the patient was treated with isoniazid, rifampin and ethambutol. two months after drug therapy, marked improvement was developed.

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عنوان ژورنال:
archives of pediatric infectious diseases

جلد ۴، شماره ۱، صفحات ۰-۰

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